Which of the followings are active substances present in granules of mast cells?

A、Histamine, leukotriene and heparin;

B、Histamine, eosinophil chemotactic factor and leukotriene;

C、Histamine, heparin and eosinophil chemotactic factor ;

D、Heparin, leukotriene and eosinophil chemotactic factor