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Selectin family and its member
Selectin family and its member
发布时间:
2025-02-04 00:34:56
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答案:
选择素家族及其成员是是一类异亲型结合、Ca
2
依赖的细胞粘着分子,能与特异糖基识别并结合。在白细胞与内皮细胞粘附,炎症发生以及淋巴细胞归巢中发挥重要作用。选择素家族有L-选择素、E-选择素、P-选择素三个成员,其中E、L、P分别表示最初分离获得这三个选择素的内皮细胞、白细胞和血小板。各成员膜外区有较高的同源性和结构类似性,但穿膜区和胞浆区没有同源性。
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