An enteric-coated dosage form can be used to avoid all the following problems possible from oral drug administration EXCEPT

A、irritation to the gastric mucosa with nausea and vomiting;
B、formation of nonabsorbable drug-food complexes ;
C、unpleasant taste of the drug ;
D、destruction of the drug by gastric acid or digestive enzymes;
E、variability in absorption caused by fluctuations in gastric emptying time